Effects of Using Substance

Different substances affect the body in different ways, but all psychoactive drugs have chemical effects in the brain. And we all have heard that any sort of substance is going to make you addicted if it’s taken in excessive amount.

The short-term effects that arise in drug users depend on the consumption and the power of the drug. Drugs can influence a person’s thinking, mood, energy level, and perception. They may harm motor functioning, hinder with decision-making and problem-solving, and diminish self awareness.

The long-term effect of drug and alcohol abuse can have a terrible physical and mental health cost. As the body adapts to the presence of a substance, it requires increasing amounts of it to experience the desired results, a process known as tolerance. As a user continues to increase doses, physical reliance may increase. That consequently gives a growth to nasty and sometimes toxic withdrawal symptoms once the person stops using the substance.

Some common substances of abuse include alcohol, hallucinogens, opiates which create their own distinctive short-term and long term effects.


Alcohol is well-known and has become almost inextricably linked with a number of social, cultural, and religious events. When consumed in moderation, alcohol can be relatively safe, but having more than normal dose will harm you.

Short term effects:

  • Mood swings.
  • Impaired judgment.
  • Coordination issues.
  • Trouble concentrating.
  • Memory problems.
  • Slurred speech.
  • Uncontrolled eye movements.
  • Stupor.
  • Coma.
Long term effects:
  • Cirrhosis.
  • Alcoholic hepatitis.
  • Liver cancer.
  • Pancreatitis.
  • Cardiomyopathy (stretching and weakening of heart muscle).
  • Irregular heart rhythm.
  • High blood pressure.
  • Stroke.
  • Mouth and throat cancer.
  • Breast cancer.
  • Weakened immune system.
  • Irritability.
  • Suicidal ideation.


Hallucinogens, such as DMT, LSD, psilocybin (magic mushrooms), and peyote (mescaline), may all differ slightly in short-term effects and intensity of intoxication, but overall, they extract many of the same mind-altering side effects. And the long term effects are associated with nervous system toxicity.

Short term effects: 
  • Hallucinations.
  • Synesthesia, or mixing of senses.
  • Intensified perceptions.
  • Significant anxiety or depression.
  • Increased heart rate.
  • Heart palpitations.
  • Dilated pupils.
  • Blurred vision.
  • Excessive sweating.
  • Tremors.
  • Paranoia.
  • Impaired judgment.
  • Impaired motor control.
Long term effects:
  • Persistent memory impairments.
  • Psychological dysfunction.
  • Imbalance of hormone production.
  • Serotonin malfunction.
  • Sleep problems.
  • White matter damage in the brain.
  • Damage to axons, which impacts impulse conduction.
  • Decreased connectivity between brain areas.


Using opiates, such as heroin or prescription painkillers, like Vicodin, Percocet, and OxyContin, can be mainly hazardous because it often leads to respiratory depression. Heroin is usually injected or snorted (and sometimes smoked), while opiate painkillers are most often taken orally, yet may also be crushed and snorted, or mixed with liquid solution and injected. Additionally, research suggests that constant opiate abuse can lead to worsening of the white matter in the brain, which impacts behavioral regulation, stress response, and decision-making.

Short term effects:
  • Euphoria followed by apathy
  • Dysphoria, or unease.
  • Nausea.
  • Vomiting.
  • Pinpoint pupils.
  • Itching skin.
  • Inattention to the environment.
  • Slowed thinking and movements.
  • Attention problems.
  • Memory impairments.
  • Drowsiness.
  • Slurred speech.
  • Coma.
Long term effects:
  • Severe constipation and related gastrointestinal conditions (e.g., bowel obstruction, bowel perforation).
  • Sexual dysfunction.
  • Irregular menses in women.
  • Intravenous consequences:
    • Track lines or puncture marks.
    • Peripheral edema.
    • Cellulitis.
    • Abscesses.
    • Tuberculosis.
    • HIV or hepatitis virus contraction.
    • Infection of the heart lining.
  • Intranasal effects:
    • Irritation of nasal lining.
    • Perforation of nasal septum.
    • Nasal bleeding.

Kindly tell this to people around you, who are drug abusers. It gives a healing pleasure while taking drugs and it makes us relax, but the results are very dangerous. It can take your life too.


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